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A marker gene is a gene used in nuclear biology and molecular biology to determine if a nucleic acid sequence has been successfully inserted into an organism's DNA1. There are two sub-types of these marker genes:
- Selectable marker: This type of marker protects the organism from a selective agent that would normally kill it or prevent its growth. For example, antibiotics are the most common selective agents used. In a transformation reaction, only one in several million to billion cells may take up DNA. Rather than checking every single cell, scientists use a selective agent to kill all cells that do not contain the foreign DNA, leaving only the desired ones1.
In the context of genetic engineering, a marker gene is transferred with the desired gene to enable scientists to identify which cells have been successfully altered and now contain recombinant DNA2. Antibiotic-resistant genes were once commonly used as marker genes2.
Learn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.en.wikipedia.org/wiki/Marker_genewww.savemyexams.com/a-level/biology/cie/22/revi…en.wikipedia.org/wiki/Genetic_marker- People also ask
Genetic Marker - National Human Genome Research Institute
Web6 days ago · Definition. A genetic marker is a DNA sequence with a known physical location on a chromosome. Genetic markers can help link an inherited disease with the responsible gene. DNA segments close to each other on a chromosome tend to be …
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Genetic marker - Wikipedia
A genetic marker is a gene or DNA sequence with a known location on a chromosome that can be used to identify individuals or species. It can be described as a variation (which may arise due to mutation or alteration in the genomic loci) that can be observed. A genetic marker may be a short DNA sequence, such as a sequence surrounding a single base-pair change (single nucleotide polymorphism, SNP), or a long one, like minisatellites.
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Web6 days ago · Definition. A marker (largely synonymous with the word “landmark” and often referred to as a genomic marker or a genetic marker) is a DNA sequence, typically with …
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WebAug 17, 2020 · These characteristic patterns in the chemical bases that make up DNA are referred to as markers. DNA markers don't, by themselves, identify the gene responsible for the disease or trait; but …
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WebA marker is a gene that is transferred with the desired gene to enable scientists to identify which cells have been successfully altered and now contain recombinant …
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WebSep 7, 2020 · “A marker gene is a known DNA sequence located nearer to the target gene with detectable and inherited properties.” Marker genes are applicable in the …
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