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- Possible causes and triggers of restless legs at night include12345:
- Low levels of iron in the brain
- Imbalance of dopamine
- Genetic component (about 60% of people with RLS have a family member with the condition)
- Nerve damage in the legs from diabetes, kidney problems, or other health conditions
- Certain medications
- Stress
- Alcohol, caffeine, and nicotine
- Pregnancy or hormonal changes
- Sleep deprivation or sleep disorders
Learn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.Experts believe that low levels of iron in the brain may be responsible for RLS. An imbalance of dopamine is also believed to contribute. About 60% of people with restless legs have a family member with the condition, indicating a strong genetic component.www.helpguide.org/wellness/sleep/restless-leg-syn…The cause of RLS is still unknown. Some cases are believed to be inherited. Some cases have been linked with nerve damage in the legs from diabetes, kidney problems, iron deficiency, certain medicines, pregnancy, sleep disorders, and alcoholism.www.hopkinsmedicine.org/health/conditions-and-di…Triggers are things that make your RLS symptoms worse. Possible triggers can vary but could include: Alcohol. Caffeine. Nicotine. Certain medications. Stress. If you experience these triggers or use/take them before you rest or go to bed, they’re more likely to set off your symptoms.my.clevelandclinic.org/health/diseases/9497-restle…If you're experiencing restless legs at night, a variety of factors could be contributing to your symptoms. Having underlying health conditions, eating certain foods, or being pregnant may all lead to the onset of restless legs.www.health.com/restless-legs-causes-7972584RLS also appears to be related to or accompany the following factors or underlying conditions:
- End-stage renal disease and hemodialysis
- Neuropathy (nerve damage)
- Sleep deprivation and other sleep conditions such as sleep apnea
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