Alexa Bliss and Nikki Cross formed a tag team in 2019 and won the WWE Women's Tag Team Championship twice. They eventually split up in 2020 after Bliss became influenced by The Fiend.
Alexa Bliss and Braun Strowman were partners in the Mixed Match Challenge in 2018 and had a friendly relationship. However, their friendship turned sour in 2020 when Strowman became The Fiend's target and Bliss became his ally.
Alexa Bliss and Randy Orton started a feud in late 2020, after Orton set The Fiend on fire at TLC 2020. Bliss tormented Orton with various mind games and supernatural attacks, leading to a match at Fastlane 2021, where The Fiend returned and helped Bliss defeat Orton.
Alexa Bliss and Nia Jax were best friends in NXT and on the main roster, until Bliss turned on Jax in 2018 and mocked her for her weight and appearance. They had a heated feud over the Raw Women's Championship, which Jax won at WrestleMania 34.
Alexa Bliss and Mickie James were allies in 2017, when Bliss recruited James to help her against the other women of Raw. However, Bliss later betrayed James and insulted her for her age and legacy. They fought over the Raw Women's Championship at TLC 2017 and on Raw.