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- Read-across is a method used in chemical risk assessment to predict the properties of a substance based on the properties of a similar substance123.Examples of read-across include123:
- Qualitative read-across, which is a yes or no indication as to whether the target substance is expected to elicit a particular effect, as observed with the analogue(s).
- Quantitative read-across, which obtains a numerical value for a particular property or endpoint based on information available for the analogue(s).
- Serial registration in China, where read-across is widely used. Enterprises shall provide physicochemical data of each substance as well as a complete set of data that consists of health toxicological data and eco-toxicological data of new substances in the group.
Learn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.For example, qualitative read-across could be a yes or no indication as to whether the target substance is expected to elicit a particular effect, as observed with the analogue (s). With quantitative read-across, a numerical value is obtained for a particular property or endpoint based on information available for the analogue (s).www.canada.ca/en/health-canada/services/chemic…Take new substance registration in China for example, read-across is widely used in serial registration. When carrying out serial registration, enterprises shall provide physicochemical data of each substance as well as a complete set of data that consists of health toxicological data and eco-toxicological data of new substances in the group.www.cirs-group.com/en/chemicals/interpretation-o…Example for an identity of the source substance which is clear and unambiguous and allows a meaningful read-across assessment A mono-constituent substance consists of 97.0-99.5% (typical 99.0%) Substance A and 0.5- 3.0% identified impurities5 (typical 1.0% water).www.echa.europa.eu/documents/10162/17221/raaf… - People also ask
READ ACROSS definition and meaning | Collins English Dictionary
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