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- Read-across is a method used in chemical risk assessment to predict the properties of a substance based on the properties of a similar substance123.Examples of read-across include123:
- Qualitative read-across, which is a yes or no indication as to whether the target substance is expected to elicit a particular effect, as observed with the analogue(s).
- Quantitative read-across, which obtains a numerical value for a particular property or endpoint based on information available for the analogue(s).
- Serial registration in China, where read-across is widely used. Enterprises shall provide physicochemical data of each substance as well as a complete set of data that consists of health toxicological data and eco-toxicological data of new substances in the group.
Learn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.For example, qualitative read-across could be a yes or no indication as to whether the target substance is expected to elicit a particular effect, as observed with the analogue (s). With quantitative read-across, a numerical value is obtained for a particular property or endpoint based on information available for the analogue (s).www.canada.ca/en/health-canada/services/chemic…Take new substance registration in China for example, read-across is widely used in serial registration. When carrying out serial registration, enterprises shall provide physicochemical data of each substance as well as a complete set of data that consists of health toxicological data and eco-toxicological data of new substances in the group.www.cirs-group.com/en/chemicals/interpretation-o…Example for an identity of the source substance which is clear and unambiguous and allows a meaningful read-across assessment A mono-constituent substance consists of 97.0-99.5% (typical 99.0%) Substance A and 0.5- 3.0% identified impurities5 (typical 1.0% water).www.echa.europa.eu/documents/10162/17221/raaf… - People also ask
READ ACROSS definition and meaning | Collins English Dictionary
WEB4 days ago · read across. phrasal verb. If you read across from one thing to another, you think or conclude that what is true of the first thing is also true of the second thing. [mainly business] It is dangerous to read across from one bank to the whole sector. [VP from n to n]
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READ-ACROSS Definition & Meaning | Dictionary.com
WEBnoun. a correlation or relationship between two separate things. Discover More. Example Sentences. Shock at what the government considers dangerous and high risk could be …
- Studies of read across example
Introduction to Read-across: Principles, Techniques and ... - US …
WEBJul 29, 2022 · This presentation will provide an overview of common principles and techniques employed in read-across, outlining available frameworks and guidelines for …
Examples of 'read-across' in a sentence - Collins Online Dictionary
WEBExamples from Collins dictionaries. It is dangerous to read across from one bank to the whole sector. There are some structural issues that don't read across to the British market.
- Whenever category approach read-across is used, properties of a target substance are predicted from properties of source substances within the category. The category hypothesis should apply in an unambiguous manner to all the category members. Only category members that are covered by the category hypothesis can be involved in the read-across. This...
2.6 Read-Across Toxicity Predictions - GitHub Pages
WEBThe method of read-across represents one type of computational approach that is commonly used to predict a chemical’s toxicological effects using its properties. Other types of approaches that you will hear commonly used …
WEBa list of the endpoints that are to be read-across; vi. a data matrix; vii. a conclusion on the applicability of the proposed read-across approach. 3.2. Make a clear read-across …
Introduction to Read-across: Principles, Techniques and …
WEBJul 29, 2022 · Overview. Read-across is a popular methodology that allows predictions to be made for a variety of endpoints using experimental data from a source analogue (s) …
Meaning of "read-across" in the English dictionary - educalingo
WEBIts implementation is based on analysing how often the term «read-across» appears in digitalised printed sources in English between the year 1500 and the present day. …
Use of analogues and read-across in risk assessment
WEBSelection of analogues. Addressing data needs through read-across. Read-across is one approach frequently used in the risk assessment of substances that lack information on …
Read-Across Methodology in Toxicological Risk Assessment
WEBJun 19, 2021 · Abstract. Grouping approaches like read-across (RAx) are one of the most widely used methods to fill data gaps in human risk assessment. In a RAx approach, in …
Interpretation on How to Properly Adopt Read-across Approach …
WEBApr 20, 2022 · Take new substance registration in China for example, read-across is widely used in serial registration. When carrying out serial registration, enterprises shall …
Overview on guidance documents and read-across workflows
WEBNov 28, 2019 · Read-across is one of the most frequently used alternative tools for hazard assessment, in particular for complex endpoints such as repeated dose or …
Chemical Safety Assessment Using Read-Across: Assessing the …
WEBMay 8, 2015 · The aim of the suggested strategy for chemical read-across is to show how a traditional read-across based on structural similarities between source and target …
WEBRead-across illustrative example Example 1 corresponds to the source substance, undergo rapid hydrolysis in contact with water producing the same acid X and very …
WEBIn the near future, illustrative examples for broad public access could be prepared. Introduction. Read-across has garnered much attention, since it may be used as an …
READ ACROSS definition in American English - Collins Online …
WEBnoun. a correlation or relationship between two separate things. Collins English Dictionary. Copyright © HarperCollins Publishers. Examples of 'read-across' in a sentence. read …
Exploring Current Read-across Applications and Needs Among …
WEBOne of the most well-established NAMs is a data gap-filling technique known as read-across. Read-across is the process of using known information from one or more …
WEBStep-by-step example for predicting Ames mutagenicity by making use of read-across. Background. Keywords. Objectives. Specific Aims. Read-across. The exercise. …
Read-across example - ECHA - Europa - Yumpu
WEBJul 29, 2013 · Example 1<br /> <strong>Read</strong>-<strong>across</strong> illustrative <strong>example</strong><br /> DISCLAIMER<br /> This document …
Metabolomics as read-across tool: An example with 3 …
WEBNov 1, 2019 · •. A read across from 2-aminoethanol (MEA) to 3-aminopropanol (3AP) is presented. •. Metabolomics is used to add biological information to support the read …
What do 'Read Across', 'Drill Deep' & '6 Panels' mean in GM's …
WEBJun 7, 2011 · Read across is sheet to complete to verify that you have considered if this defect or root cause of the a defect can impact any other similar part or manufacturing …
Former leaders have been jailed or charged all over the world
WEBAug 26, 2022 · Former President Trump declared himself a "very innocent man" on Thursday and said the U.S. has "has gone to hell" after becoming the first American …
Grouping of substances and read-across - ECHA
WEBECHA has developed an illustrative example of a grouping of substances and read-across approach to support companies in complying with their obligations under REACH. The …
Tracking extreme heat risk alerts across the US | CNN
WEBMay 26, 2024 · Published 1:00 AM EDT, Sun May 26, 2024. Link Copied! CNN —. High temperatures affect public health across wide swaths of the United States each …
Global report reveals major gaps in menstrual health and hygiene …
WEB5 days ago · Worldwide, only 2 out of 5 schools (39%) provide menstrual health education. This increases in secondary schools, with 84% of secondary schools in Central and …
Read Across America Day, 2024 - Federal Register
WEBMar 6, 2024 · This Read Across America Day, we must also acknowledge a difficult truth—that our children are growing up in a country where some extremist politicians are …
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