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- Read-across is a method used in chemical risk assessment to predict the properties of a substance based on the properties of a similar substance123.Examples of read-across include123:
- Qualitative read-across, which is a yes or no indication as to whether the target substance is expected to elicit a particular effect, as observed with the analogue(s).
- Quantitative read-across, which obtains a numerical value for a particular property or endpoint based on information available for the analogue(s).
- Serial registration in China, where read-across is widely used. Enterprises shall provide physicochemical data of each substance as well as a complete set of data that consists of health toxicological data and eco-toxicological data of new substances in the group.
Learn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.For example, qualitative read-across could be a yes or no indication as to whether the target substance is expected to elicit a particular effect, as observed with the analogue (s). With quantitative read-across, a numerical value is obtained for a particular property or endpoint based on information available for the analogue (s).www.canada.ca/en/health-canada/services/chemic…Take new substance registration in China for example, read-across is widely used in serial registration. When carrying out serial registration, enterprises shall provide physicochemical data of each substance as well as a complete set of data that consists of health toxicological data and eco-toxicological data of new substances in the group.www.cirs-group.com/en/chemicals/interpretation-o…Example for an identity of the source substance which is clear and unambiguous and allows a meaningful read-across assessment A mono-constituent substance consists of 97.0-99.5% (typical 99.0%) Substance A and 0.5- 3.0% identified impurities5 (typical 1.0% water).www.echa.europa.eu/documents/10162/17221/raaf… - People also ask
WebJul 29, 2022 · This presentation will provide an overview of common principles and techniques employed in read-across, outlining available frameworks and guidelines for best practices in conducting and documenting read-across justifications. Examples of the …
See results only from cfpub.epa.govIntroduction to Read-across…
Overview. Read-across is a popular methodology that allows predictions to …
Web4 days ago · read across. phrasal verb. If you read across from one thing to another, you think or conclude that what is true of the first thing is also true of the second thing. …
Webnoun. a correlation or relationship between two separate things. Discover More. Example Sentences. Shock at what the government considers dangerous and high risk could be …
WebExamples from Collins dictionaries. It is dangerous to read across from one bank to the whole sector. There are some structural issues that don't read across to the British market.
WebJun 19, 2021 · A. Bitsch. 124 Accesses. Abstract. Grouping approaches like read-across (RAx) are one of the most widely used methods to fill data gaps in human risk …
WebRead-across illustrative example Example 1 corresponds to the source substance, undergo rapid hydrolysis in contact with water producing the same acid X and very …
Weba list of the endpoints that are to be read-across; vi. a data matrix; vii. a conclusion on the applicability of the proposed read-across approach. 3.2. Make a clear read-across …
WebDefine read-across. read-across synonyms, read-across pronunciation, read-across translation, English dictionary definition of read-across. n a correlation or relationship …
WebMay 8, 2015 · The aim of the suggested strategy for chemical read-across is to show how a traditional read-across based on structural similarities between source and target …
Web‘Read-across and grouping’, or ‘read-across’, is one of the most commonly used alternative approaches for data gap filling in registrations submitted under the REACH Regulation. …
2.6 Read-Across Toxicity Predictions - GitHub Pages
WebThe method of read-across represents one type of computational approach that is commonly used to predict a chemical’s toxicological effects using its properties. Other …
Exploring Current Read-across Applications and Needs Among …
WebOne of the most well-established NAMs is a data gap-filling technique known as read-across. Read-across is the process of using known information from one or more …
WebIn the near future, illustrative examples for broad public access could be prepared. Introduction. Read-across has garnered much attention, since it may be used as an …
Interpretation on How to Properly Adopt Read-across Approach …
WebApr 20, 2022 · Take new substance registration in China for example, read-across is widely used in serial registration. When carrying out serial registration, enterprises shall provide …
Use of analogues and read-across in risk assessment
WebSelection of analogues. Addressing data needs through read-across. Read-across is one approach frequently used in the risk assessment of substances that lack information on …
READ ACROSS definition in American English - Collins Online …
Webnoun. a correlation or relationship between two separate things. Collins English Dictionary. Copyright © HarperCollins Publishers. Examples of 'read-across' in a sentence. read …
Meaning of "read-across" in the English dictionary - educalingo
WebIts implementation is based on analysing how often the term «read-across» appears in digitalised printed sources in English between the year 1500 and the present day. …
WebStep-by-step example for predicting Ames mutagenicity by making use of read-across. Background. Keywords. Objectives. Specific Aims. Read-across. The exercise. …
Read-across example - ECHA - Europa - Yumpu
WebJul 29, 2013 · Example 1<br /> <strong>Read</strong>-<strong>across</strong> illustrative <strong>example</strong><br /> DISCLAIMER<br /> This document …
What do 'Read Across', 'Drill Deep' & '6 Panels' mean in GM's …
WebJun 7, 2011 · Read across is sheet to complete to verify that you have considered if this defect or root cause of the a defect can impact any other similar part or manufacturing …
GM's "Read Across" Process that shares 8D results across …
WebOct 11, 2006 · Feb 10, 2007. #2. Re: "Read Across" Process that shares 8D results across divisions and locations - See. Our tracking matrices for corrective actions and preventive …
Grouping of substances and read-across - ECHA
WebECHA has developed an illustrative example of a grouping of substances and read-across approach to support companies in complying with their obligations under REACH. The …
Read Across America Day, 2024 - Federal Register
WebMar 6, 2024 · This Read Across America Day, we must also acknowledge a difficult truth—that our children are growing up in a country where some extremist politicians are …
Former leaders have been jailed or charged all over the world
WebAug 26, 2022 · Former President Trump declared himself a "very innocent man" on Thursday and said the U.S. has "has gone to hell" after becoming the first American …
Global report reveals major gaps in menstrual health and hygiene …
Web5 days ago · Worldwide, only 2 out of 5 schools (39%) provide menstrual health education. This increases in secondary schools, with 84% of secondary schools in Central and …
IT support workers share the oddest tech problems they've dealt …
WebPeople from across the world shared IT issues that probably weren't easy to fix ; READ MORE: ... Another example of tech with a dual purpose is one device that ended up …
Tracking extreme heat risk alerts across the US | CNN
WebMay 26, 2024 · Published 1:00 AM EDT, Sun May 26, 2024. Link Copied! CNN —. High temperatures affect public health across wide swaths of the United States each summer, …
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