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  2. A syndrome of prolonged, severe chest pain was first described in medical literature in 1912 by James Bryan Herrick, who attributed the syndrome to coronary thrombosis, the development of a clot in a major blood vessel serving the heart. As a result, the disorder was termed coronary thrombosis or coronary occlusion (blockage of a coronary artery).
    www.britannica.com/science/cardiovascular-disease/Myocardial-infarction
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    When was myocardial infarction first defined?Recognizing the need for such protocols in the clinical and research setting, the World Health Organization (WHO) published the first guideline for the definition of myocardial infarction in 1959. That definition was based on ischemic pain and ECG changes.
    What is a silent myocardial infarction?
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    Dr. Howard E. LeWine

    M.D. Chief Medical Editor, Harvard Health Publishing · 40 years of exp

    A silent myocardial infarction is also known as a silent heart attack. It produces no symptoms, or only produce mild symptoms that are so unremarkable that people mistake them for something else, like heartburn or a chest muscle strain. People often don’t learn that they had a heart attack until they have an electrocardiogram (ECG), a stress test or an echocardiogram and the doctor notices signs consistent with heart damage. As in traditional symptomatic heart attacks, a silent heart attack involves a blockage of blood flow to the heart. This injures and scars part of the heart muscle, leaving behind telltale signs.
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    What causes a myocardial infarction?Most myocardial infarctions are due to underlying coronary artery disease, the leading cause of death in the United States. With coronary artery occlusion, the myocardium is deprived of oxygen. Prolonged deprivation of oxygen supply to the myocardium can lead to myocardial cell death and necrosis.
    What is a myocardial infarction (MI)?See all... See more... Myocardial infarction (MI), colloquially known as “heart attack,” is caused by decreased or complete cessation of blood flow to a portion of the myocardium. Myocardial infarction may be “silent” and go undetected, or it could be a catastrophic event leading to hemodynamic deterioration and sudden death.
    Who invented cardiac infarction?Liebowitz, in fact, gives equal credit to Polish researchers Obrastzow and Straschesko in 1910, “for having initiated the definitive understanding of cardiac infarction as a clinically recognizable morbid entity, which was later acknowledged to be a very common condition and of paramount statistical importance” (ibid., 11).
    What is a heart attack (myocardial infarction)?What is a heart attack? A heart attack (myocardial infarction) is an extremely dangerous condition that happens because you don’t have enough blood flow to some of your heart muscle. This lack of blood flow can occur because of many different factors but is usually related to a blockage in one or more of your heart’s arteries.
     
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    Myocardial infarction - Wikipedia

    Myocardial infarction; Other names: Acute myocardial infarction (AMI), heart attack: A myocardial infarction occurs when an atherosclerotic plaque slowly builds up in the inner lining of a coronary artery and then suddenly ruptures, causing catastrophic thrombus formation, totally occluding the artery and preventing … See more

    A myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops in one of the coronary arteries of the heart, causing infarction (tissue … See more

    The most prominent risk factors for myocardial infarction are older age, actively smoking, high blood pressure, diabetes mellitus, and total cholesterol and high-density lipoprotein levels. Many risk factors of myocardial infarction are shared with See more

    Criteria
    A myocardial infarction, according to current consensus, is defined by elevated cardiac See more

    Myocardial infarction (MI) refers to tissue death (infarction) of the heart muscle (myocardium) caused by ischemia, the lack of oxygen delivery to myocardial tissue. It is a type of See more

    Chest pain that may or may not radiate to other parts of the body is the most typical and significant symptom of myocardial infarction. It might … See more

    Atherosclerosis
    The most common cause of a myocardial infarction is the rupture of an atherosclerotic plaque on an artery supplying heart … See more

    There is a large crossover between the lifestyle and activity recommendations to prevent a myocardial infarction, and those that may be … See more

     
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  5. Evolution of Myocardial Infarction and its Biomarkers: A Historical ...

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  7. Myocardial Infarction - StatPearls - NCBI Bookshelf

    WebAug 8, 2023 · Myocardial infarction (MI), colloquially known as "heart attack," is caused by decreased or complete cessation of blood flow to a portion of the myocardium. Myocardial infarction may be"silent," and …

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  10. A Tale of Coronary Artery Disease and Myocardial …

    WebJan 5, 2012 · In 1879, the pathologist Ludvig Hektoen concluded that myocardial infarction is caused by coronary thrombosis “secondary to sclerotic changes in the coronaries.” 6 In 1910, two Russian...

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    WebMay 4, 2020 · Acute myocardial infarction (MI) historically is defined as a clinical syndrome that meets a certain set of criteria, usually a combination of symptoms, electrocardiographic changes, and cardiac biomarkers in …

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    WebDec 2, 2022 · When damage or death to part of the heart muscle occurs due to ischemia, it’s called a heart attack, or myocardial infarction (MI). About every 40 seconds, someone in the United States has a heart attack. …

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