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- Neurofibromatosis type 1 (NF1) is an inherited condition that can cause various symptoms, including neurofibromas, cutaneous and skeletal disfigurement, and neurological conditions. While it doesn't directly affect life expectancy for most people, complications can arise, and in 8-13% of cases, neurofibromas may transition into cancer, which can be fatal123. People with NF1 also have a greater chance of dying from some cancer types than those without the condition4.Learn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.Neurofibromas may occur and can sometimes cause many dependent neurological conditions and cutaneous and skeletal disfigurement. Depression and social anxiety may occur as a result of disabilities caused by the condition Neurofibromas may, in 8-13% of cases, transition into cancer, which can be fatalen.wikipedia.org/wiki/Neurofibromatosis_type_IBetween 5% and 10% of patients with NF1 will develop a malignant tumor at some point in their lives. More rare tumors, like tumors of the adrenal gland, can cause a drastic rise in blood pressure and be damaging as well. In rare cases, NF1 can also be associated with other cancers, such as breast cancer or leukemia.www.mdanderson.org/cancerwise/what-is-neurofibr…Overall, NF1 doesn’t directly affect your life expectancy if your symptoms are mild. Most people experience an average life expectancy. Complications, while less common, may affect your prognosis, especially if you have numerous tumors that can’t safely be surgically removed or if your tumors develop into cancer.my.clevelandclinic.org/health/diseases/14422-neur…An inherited condition called neurofibromatosis type 1 (NF1) is linked to the development of more types of cancer than previously realized, according to results from a new study. People with NF1 also have a greater chance of dying from some cancer types than people without the condition, the study found.www.cancer.gov/news-events/cancer-currents-blog…
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WEBBoth NF1 and NF2 are genetic conditions that affect nerve tissue, but NF1 and NF2 have different symptoms. NF1, far more common than NF2, is characterized by brownish cafe-au-lait spots on the skin and tumors …
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WEBUpdated on February 26, 2022. Medically reviewed by Nicholas R. Metrus, MD. Print. Neurofibromatosis is a genetic nervous system disorder that causes tumors to grow around nerves. There are three types of …
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