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In this systematic review, a comprehensive list of tests for the detection of HRD was identified and compared regarding HRD …

Dec 26, 2024 · Homologous recombination deficiency (HRD) is considered a universal and effective sign of a tumor’s sensitivity to …

Feb 21, 2025 · The use of poly(ADP-ribose) polymerase inhibitors (PARPi) revolutionized the treatment of BRCA-mutated cancers. …

Aug 1, 2025 · Homologous recombination deficiency (HRD) is a genomic feature present in some malignant neoplasms and is …

Jun 13, 2025 · Homologous recombination deficiency (HRD) is a genomic feature present in some malignant neoplasms and is …

Mar 1, 2023 · The repair of DNA double-stranded breaks relies on the homologous recombination repair pathway and is critical to cell …

We examine the copy number and structural alterations that often accompany the genome instability that results from HRD, describe …

Mar 11, 2022 · Overall, this publication provides additional perspectives for scientist, physician, laboratory, and patient communities …

Homologous recombination deficiency (HRD) testing has expanded from BRCA germline testing to encompass comprehensive …

Nov 29, 2023 · In this systematic review, a comprehensive list of tests for the detection of HRD was identified and compared …