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Homologous recombination repair (HRR) mutation in de novo …
Mar 2, 2026 · We sought to understand the prognostic significance of HRR alterations in metastatic prostate cancer. Methods: In this …
Homologous recombination repair genetic testing variables and ...
Dec 2, 2025 · Abstract Background Evidence on homologous recombination repair (HRR) mutation prevalence in prostate cancer …
Management of advanced prostate cancer with germline or ... - UpToDate
Jun 11, 2025 · First-line treatment of metastatic CRPC with BRCA Tables Management of advanced prostate cancer with HRR …
Homologous recombination repair gene mutation (HRRm) testing …
Jan 29, 2024 · Homologous recombination repair gene mutation (HRRm) testing patterns and treatment selection from a real-world …
Homologous Recombination Repair Gene Mutations in Prostate Cancer ...
May 20, 2024 · This comprehensive overview aims to increase the clinical implementation of HRR gene mutation testing and inform …
Prostate cancer is the most common solid organ cancer in men and is associated with substantial mortality.1 While survival rates are …
Treatment patterns and outcomes in metastatic castration-resistant ...
Feb 26, 2024 · Abstract Background Although germline BRCA mutations have been associated with adverse outcomes in prostate …
This comprehensive overview aims to increase the clinical implementation of HRR gene mutation testing and inform future efforts in …
Niraparib and abiraterone acetate plus prednisone for HRR-deficient ...
Oct 7, 2025 · In the randomized phase 3 AMPLITUDE trial, patients with HRR-deficient mCSPC experienced longer progression-free …
Comparative efficacy of first-line treatments for HRR-mutated ...
May 2, 2026 · Comparative efficacy of first-line treatments for HRR-mutated metastatic castration-resistant prostate cancer： a …
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