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Paneth cells as the cornerstones of intestinal and organismal …
WEBDec 27, 2022 · Paneth cells are the main producers of AMPs in the gastrointestinal tract, making them key players in sensing and controlling the microbiome composition. …
- DOI: 10.15252/emmm.202216427
- Published: 2023/02
- Publication: EMBO Mol Med. 2023 Feb; 15(2): e16427.
Paneth cells, antimicrobial peptides and maintenance of ... - Nature
WEBMar 22, 2011 · The Paneth cells in the endothelium of the small intestine produce a large array of antimicrobial proteins that help set this balance and protect the host from …
- Author: Charles L. Bevins, Nita H. Salzman
- Publish Year: 2011
The Paneth Cell: The Curator and Defender of the Immature …
WEBApr 3, 2020 · This review will provide an up to date and comprehensive look at Paneth cell ontogeny, the impact Paneth cells have on the host-microbial axis in the immature …
Frontiers | The Paneth Cell: The Curator and Defender of the …
WEBApr 2, 2020 · Paneth cells are secretory epithelial cells that produce antimicrobial peptides and immunomodulatory proteins in the small intestinal crypts. They are …
- Studies of paneth cell
Paneth cells and their multiple functions - PubMed
WEBThis review aims to address the main characteristics of Paneth cells, highlighting their multiple functions and the importance of their preservation to ensure bowel homeostasis. …
Paneth cells in intestinal physiology and pathophysiology
WEBNov 11, 2017 · Paneth cells are important secretory cells in the small intestinal mucosa. They are found as metaplastic cells in several other locations. Important secretory …
The Paneth Cell: The Curator and Defender of the Immature …
WEBApr 3, 2020 · One particular type of intestinal epithelial cell, the Paneth cell, was first discovered by Gustav Schwalbe in the late 19th century based on the eosinophilic …
Paneth cells as the cornerstones of intestinal and organismal …
WEBDec 27, 2022 · Paneth cells are versatile secretory cells located in the crypts of Lieberkühn of the small intestine. In normal conditions, they function as the …
Paneth’s cell | Gastric Mucosa, Intestinal Crypts
WEBPaneth’s cell, specialized type of epithelial cell found in the mucous-membrane lining of the small intestine and of the appendix, at the base of tubelike depressions known as Lieberkühn glands. Named for the 19th …
Paneth cells: Current Biology - Cell Press
WEBJun 16, 2014 · What are Paneth cells and when were they discovered? Paneth cells, along with goblet cells, enterocytes, tuft cells and enteroendocrine cells, represent the …
Paneth cells: maestros of the small intestinal crypts - PubMed
WEBPaneth cells are highly specialized epithelial cells of the small intestine, where they coordinate many physiological functions. First identified more than a century ago on the …
Paneth Cells: Definition, Functions And Role In The Intestine
WEBJun 2, 2024 · Paneth cells are one of the main cell types of the epithelium, which provide host defense against microbes in the small intestine. When these Paneth cells are …
Paneth cells as the cornerstones of intestinal and organismal …
WEBDec 27, 2022 · Paneth cells are versatile secretory cells located in the crypts of Lieberkühn of the small intestine. In normal conditions, they function as the …
Intestinal Paneth cell differentiation relies on asymmetric
WEBNov 24, 2023 · Paneth cells form a major element of the niche microenvironment providing various growth factors to orchestrate intestinal stem cell homeostasis, such as Wnt3. …
Paneth Cells during Viral Infection and Pathogenesis - PMC
WEBApr 26, 2018 · Paneth cells are major secretory cells located in the crypts of Lieberkühn in the small intestine. Our understanding of the diverse roles that Paneth …
Pathology Outlines - Anatomy & histology
WEBOct 29, 2021 · Paneth cells. They have a triangular shape with densely eosinophilic cytoplasmic granules and basally located nuclei, as opposed to enteroendocrine cells …
Paneth cells: the hub for sensing and regulating intestinal flora
WEBPaneth cells, as one of the major producers of antimicrobial peptides in the intestine under steady-state conditions, play a vital role in regulating intestinal flora. Many studies …
A single-cell survey of the small intestinal epithelium | Nature
WEBNov 8, 2017 · Here we perform a scRNA-seq survey of 53,193 epithelial cells of the mouse small intestine in homeostasis and during infection. We identify gene signatures, key …
Azathioprine promotes intestinal epithelial cell differentiation into ...
WEBJun 5, 2024 · Paneth cells (PCs) which reside at the base of intestinal crypts have a long lifespan (> 30 days) and play a multifaceted role in mucosal immunity and intestinal …
From birth to death: The hardworking life of Paneth cell in the …
WEBMar 10, 2023 · Paneth cells are a group of unique intestinal epithelial cells, and they play an important role in host-microbiota interactions. At the origin of Paneth cell life, several …
Paneth cells constitute the niche for Lgr5 stem cells in intestinal ...
WEBNov 28, 2010 · A new study shows that Paneth cells have an essential role for intestinal crypt and stem cell maintenance by supplying essential niche signals to the Lgr5 …
Paneth cells: their role in innate immunity and inflammatory disease
WEBWe shall review research showing how Paneth cells, and evolutionarily conserved innate immune mechanisms, are emerging as key mediators of intestinal mucosal defence.
Paneth Cells in Intestinal Homeostasis and Tissue Injury - PMC
WEBJun 20, 2012 · Paneth cells are found in the small intestine yet not in the colon where otherwise uncharacterized CD24 + cells are intermingled with Lgr5 + stem cells similar …
- Some results have been removed