marfey's reagent - Search
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  2. FDAA is 1-fluoro-2-4-dinitrophenyl-5-L-alanine amide, also called Marfey's reagent. The compound reacts with primary amines and is used as a derivatization reagent for UV detection in liquid chromatography methods. The reagent provides for detection at 340nm with nanomole sensitivity.

    FDAA (Marfey's Reagent) (1-fluoro-2-4-d…

    www.thermofisher.com/order/catalog/product/48895
    Marfey’s reagent, 1-fluoro-2,4-dinitrophenyl-5+alanine amide reacts (Scheme l), with the optical isomers of amino acids to form diastereomeric N-aryl derivatives which can be separated by conventional HPLC methods.

    (PDF) Application of marfey's reagent in …

    www.academia.edu/14985990/Application_of_marf…
     
  3. People also ask
    What is marfey's reagent used for?This article describes some of the uses of Marfey's reagent, 1-fluoro-2,4-dinitrophenyl-5-L-alanine amide (FDAA), a pre-column derivatizing reagent for the separation of enantiomeric isomers of amino acids and amine compounds. An introduction to the basic implementation of this reagent and its historical development are presented.

    Marfey's reagent: Past, present, and future uses of 1‐fluoro‐2,4

    analyticalsciencejournals.onlinelibrary.wiley.com
    Can marfey's reagent be used for enantioseparation of amino groups?The present paper assesses and reviews applications of Marfey’s reagent and its chiral variants (i.e. other FDNP reagents) for enantioseparation of certain amino group containing drugs/amino acids, and to provide some case studies on enantiomeric separations that are important for the pharmaceutical industry.

    Assessment and application of Marfey’s reagent and analogs

    analyticalsciencejournals.onlinelibrary.wiley.com
    Can marfey's reagent be used for preparing CSPs for direct enantiomeric resolution?Use of MR for preparing CSPs for direct enantiomeric resolution has also been included. The present paper describes characteristics and application of Marfey's reagent (MR) including general protocols for synthesis of the reagent and diastereomers along with advantages, disadvantages and the required precautions.

    Marfey's reagent for chiral amino acid analysis: a review

    pubmed.ncbi.nlm.nih.gov
    What is FDAA (marfey's reagent)?FDAA (Marfey's Reagent) (1-fluoro-2-4-dinitrophenyl-5-L-alanine amide) Catalog number:48895 Related applications:Protein Assays & Analysis Technical SupportCustomer Service Catalog Number 48895 Unit Size 50 mg Price (USD) Price: 140.00 Online price: 133.65 Your price:Sign In Availability Quantity Save to listAdd to cart Catalog Number Unit Size

    FDAA (Marfey's Reagent) (1-fluoro-2-4-dinitrophenyl-5-L-alanine amide)

    thermofisher.com
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  4. PubMed
    https://pubmed.ncbi.nlm.nih.gov/15503232

    Marfey's reagent for chiral amino acid analysis: a review

    See results only from pubmed.ncbi.nlm.nih.gov
     
  5. Thermo Fisher Scientific
    https://www.thermofisher.com/order/ca…

    FDAA (Marfey's Reagent) (1-fluoro-2-4-dinitrophenyl-5 …

    WEBThermo Scientific Pierce Marfey's Reagent (FDAA) reacts with primary amines to enable the quick and easy separation and quantitation of optical isomers of amino acids by reverse-phase chromatography. FDAA is 1 …

  6. Studies of marfey's reagent
    ScienceDirect
    Review Use of Marfey's reagent and analogs for chiral amino acid analysis: Assessment and applications to natural products and biological systems☆
    The present paper describes an updated knowledge and status on Marfey's reagent (MR), 1-fluoro-2,4-dinitrophenyl-5-l-alanine amide (FDNP-l-Ala-NH2). The reagent is used for pre-column derivatization of amino acids followed by HPLC separation of the
    Published: 2011/11/01
    Cited By: 0
    Keywords: Ac acetyl; A…
    analyticalsciencejournals.onlinelibrary.wiley.com
    Assessment and application of Marfey’s reagent and analogs in enantioseparation: a decade’s perspective
    Of the various methods available for high-performance liquid chromatography separation of enantiomers (of e.g. amino acids and amino group containing compounds) by the pre-column derivatization approach, use of Marfey’s reagent has been most successful
    Author: Sonika Sethi, J…
    Published: 22 Septem…
    Cited By: 14
    analyticalsciencejournals.onlinelibrary.wiley.com
    Marfey's reagent: Past, present, and future uses of 1-fluoro-2,4-dinitrophenyl-5-L-alanine amide
    This article describes some of the uses of Marfey's reagent, 1-fluoro-2,4-dinitrophenyl-5-L-alanine amide (FDAA), a pre-column derivatizing reagent for the separation of enantiomeric isomers of amino acids and amine compounds. An introduction to the
    Author: Clayton B'Hym…
    Published: 28 Januar…
    Cited By: 85
    National Center for Biotechnology Information
    LC-MS/MS-Based Separation and Quantification of Marfey’s Reagent Derivatized Proteinogenic Amino Acid DL-Stereoisomers
    There are 20 proteinogenic amino acids (AAs), which are incorporated as their L-enantiomers (except for glycine, which is achiral) in proteins. Their corresponding D-enantiomers also play important roles in many biological systems and processes [1]. The
    Author: Navid J. Ayon…
    Published: 2019/03
    DOI: 10.1007/s13361-0…
    PubMed
    Use of Marfey's reagent and analogs for chiral amino acid analysis: assessment and applications to natural products and biological systems
    The present paper describes an updated knowledge and status on Marfey's reagent (MR), 1-fluoro-2,4-dinitrophenyl-5-L-alanine amide (FDNP-L-Ala-NH(2)). The reagent is used for pre-column derivatization of amino acids followed by HPLC separation of
    Author: R Bhushan
    Published: 2011/11/01
    Keywords: National In…
    National Center for Biotechnology Information
    Discovery and Biocatalytic Application of a PLP-Dependent Amino Acid γ-Substitution Enzyme that Catalyzes C-C Bond Formation
    Nature is remarkable in building and using structurally diverse amino acids.1–2 Nonproteinogeneic amino acids (NAAs), which constitute 96% of the naturally occurring amino acids,1 are frequently incorporated into small molecules to broaden reactivity
    Author: Mengbin Chen…
    Published: 2020/06/06
    DOI: 10.1021/jacs.0c03…
    ScienceDirect
    Review Use of Marfey's reagent and analogs for chiral amino acid analysis: Assessment and applications to natural products and biological systems☆
    The present paper describes an updated knowledge and status on Marfey's reagent (MR), 1-fluoro-2,4-dinitrophenyl-5-l-alanine amide (FDNP-l-Ala-NH2). The reagent is used for pre-column derivatization of amino acids followed by HPLC separation of the
    Published: 2011/11/01
    Cited By: 105
    Page Count: 14
  7. ScienceDirect
    https://www.sciencedirect.com/science/article/pii/S1570023211003989

    Use of Marfey's reagent and analogs for chiral amino acid …

  8. MilliporeSigma
    https://www.sigmaaldrich.com/US/en/search/marfey's...

    Marfey's reagent | Sigma-Aldrich - MilliporeSigma

  9. Analytical Science Journals
    https://analyticalsciencejournals.onlinelibrary.wiley.com/...

    Assessment and application of Marfey’s reagent and …

    WEBSep 22, 2020 · The present paper assesses and reviews applications of Marfey’s reagent and its chiral variants (i.e. other FDNP reagents) for enantioseparation of certain amino group containing drugs/amino acids, …

  10. Justus-Liebig-Universität Gießen
    https://www.uni-giessen.de/.../prof/lmw/pdf-brueckner/marfeys-reagent
    [PDF]

    Marfey’s reagent for chiral amino acid analysis: A review

  11. Analytical Science Journals
    https://analyticalsciencejournals.onlinelibrary.wiley.com/...

    Marfey's reagent: Past, present, and future uses of …

    WEBJan 28, 2003 · This article describes some of the uses of Marfey's reagent, 1-fluoro-2,4-dinitrophenyl-5-L-alanine amide (FDAA), a pre-column derivatizing reagent for the separation of enantiomeric isomers of amino …

  12. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417927

    LC-MS/MS-Based Separation and Quantification of Marfey’s …

  13. PubChem
    https://pubchem.ncbi.nlm.nih.gov/.../Marfe…

    Marfey's reagent | C9H9FN4O5 | CID 5486955

    WEBMarfey's reagent | C9H9FN4O5 | CID 5486955 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, …

  14. thermofisher.com
    https://assets.thermofisher.com/TFS-Assets/LSG/...
    [PDF]

    INSTRUCTIONS FDAA, Marfey’s Reagent - Thermo Fisher …

  15. ACS Publications
    https://pubs.acs.org/doi/10.1007/s13361-0…

    LC-MS/MS-Based Separation and Quantification of …

    WEBNov 12, 2018 · In this study, we investigated the use of Marfey’s reagent (chiral) derivatization coupled with LC-MS/MS-based separation and detection of the resulting diastereomers for quantification of the 19 …

  16. Springer
    https://link.springer.com/article/10.1007/s00726-004-0118-0

    Marfey’s reagent for chiral amino acid analysis: A review

  17. Nature
    https://www.nature.com/articles/s41589-024-01619-z

    The β-subunit of tryptophan synthase is a latent tyrosine synthase

  18. PubMed
    https://pubmed.ncbi.nlm.nih.gov/21737363

    Use of Marfey's reagent and analogs for chiral amino acid …

  19. openochem.org
    https://learn.openochem.org/learn/reagents/marfeys-reagent

    Marfey's Reagent | OpenOChem Learn

  20. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335459

    Discovery and Biocatalytic Application of a PLP-Dependent …

  21. VWR
    https://us.vwr.com/store/product/17468261/piercetm...

    Pierce™ Marfey's Reagent, Thermo Scientific | VWR

  22. ScienceDirect
    https://www.sciencedirect.com/science/article/abs/...

    Use of Marfey's reagent and analogs for chiral amino acid …

  23. Taylor & Francis Online
    https://www.tandfonline.com/doi/pdf/10.1271/bbb.70371
    [PDF]

    Relative and Absolute Configuration of Antitumor Agent SW …

  24. Springer
    https://link.springer.com/chapter/10.1007/978-1-4615-2978-1_55

    Asymmetric Synthesis of Carboranyl Amino Acids with ... - Springer

  25. MilliporeSigma
    https://www.sigmaaldrich.com/IN/en/search/marfey's...

    Marfey's reagent | Sigma-Aldrich - MilliporeSigma

  26. Springer
    https://www.sigmaaldrich.com/US/en/search/marfey...

    Marfey’s reagent | Sigma-Aldrich - MilliporeSigma

  27. MilliporeSigma
    https://www.sigmaaldrich.com/US/en/search/marfeys...

    Marfeys reagent | Sigma-Aldrich - MilliporeSigma