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  2. Long-term Bisphosphonate Use Degrades Cortical Bone

    Aug 3, 2017 · The mechanism by which long-term bisphosphonate use causes atypical femoral fractures is related to degradation of toughening mechanisms inherent in healthy cortical bone.

  3. A Man With Pain in His Bones - Page 3 - Medscape

    Jan 6, 2003 · The most likely diagnosis is Paget's disease. Skeletal x-ray features of Paget's disease include increased bone density, coarse and disorganized trabeculae, cortical thickening, and sclerotic changes.

  4. Evaluating Knee Pain: The Latest in Diagnosis and Management

    The evaluation of knee pain can be challenging. In part, this stems from the fact that knee pain may arise secondary to disease within the joint, around the joint (periarticular structures, such ...

  5. Shoulder Pain: The Latest in Diagnosis and Care, Part 1

    Feb 24, 2015 · A review of the latest approaches for assessing and treating diseases and pain of the shoulder.

  6. PIK3CA -Related Overgrowth Spectrum (PROS): 5 Things to …

    Mar 19, 2024 · PROS is a group of rare congenital disorders characterized by overgrowth ranging from isolated digits to whole limbs and beyond. What conditions are in the spectrum, and how are they managed?

  7. Brain Changes in Youth Who Use Substances: Cause or Effect?

    Jan 3, 2025 · New research challenges the idea that substance use explains structural brain changes in youth, a theory that underlies current brain disease models of addiction.

  8. Outcomes After Injury to the Thumb Ulnar Collateral Ligament

    There are many ways to manage both acute and chronic thumb UCL deficiency, and controversy persists as to the best treatment options. This systematic review has demonstrated excellent clinical ...

  9. Medscape | Medicina (Kaunas) - Publication Information

    November 07, 2023 [ MEDLINE Abstract ] Effects of Increasing the Orthodontic Forces over Cortical and Trabecular Bone during Periodontal Breakdown-A Finite Elements Analysis. November 07, 2023

  10. Cannabis Use Linked to Brain Thinning in Adolescents - Medscape

    Nov 4, 2024 · Cannabis use may lead to thinning of the cerebral cortex in adolescents, research in mice and humans suggested. The multilevel study demonstrated that tetrahydrocannabinol (THC), an active ...

  11. Novel Brain Biomarker Accurately Predicts Pain Sensitivity

    Jan 29, 2025 · Predicting who will transition from acute to chronic pain is the “holy grail” of pain neuroscience. A novel biomarker signature may provide the answer.

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