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- Doesn’t cause weight gainOrencia doesn’t cause weight gain, according to clinical studies of the drug123. In fact, nausea is a common side effect of Orencia, and it may reduce your appetite, leading to weight loss1. However, weight gain is a side effect of some medications prescribed to treat the same conditions as Orencia, such as methotrexate (Trexall) and corticosteroids such as prednisone (Rayos)23. If you have unexplained weight changes during your Orencia treatment that concern you, talk with your doctor13.Learn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.No, Orencia doesn’t cause weight gain. This side effect wasn’t seen during studies of the drug. In fact, nausea is a common side effect of Orencia, and it may reduce your appetite. This could lead to weight loss. If you have unexplained weight changes during your Orencia treatment that concern you, talk with your doctor.www.healthline.com/health/drugs/orencia-side-effectsNo. People using Orencia in clinical studies didn’t report weight gain as a side effect. Weight gain can be a side effect of certain medications that treat some of the same conditions as Orencia. For example, corticosteroids, such as prednisone, and Trexall (methotrexate) can cause weight gain.www.medicalnewstoday.com/articles/drugs-orenci…Weight gain wasn’t reported as a side effect in clinical studies of Orencia. However, weight gain is a side effect of some medications prescribed to treat the same conditions as Orencia. Examples include methotrexate (Trexall) and corticosteroids such as prednisone (Rayos). If you’re concerned about weight gain and Orencia, talk with your doctor.www.healthgrades.com/drugs/orencia-side-effects
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