How does Eliquis affect INR? Eliquis can increase your international normalized ratio (INR). INR is used to describe the results of a lab test called prothrombin time (PT) .

Switching from Eliquis to warfarin: Eliquis affects INR, so that initial INR measurements during the transition to warfarin may not be useful for determining the appropriate dose of warfarin. One approach is to discontinue Eliquis and begin both a parenteral anticoagulant and warfarin at the time the next dose of Eliquis would have been taken, discontinuing the parenteral anticoagulant when INR reaches an acceptable range.