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  2. Altered gene

    Neurofibromatosis type 1 is caused by an altered gene that either is passed down by a parent or occurs at conception. The NF1 gene is located on chromosome 17. This gene produces a protein called neurofibromin that helps regulate cell growth. When the gene is altered, it causes a loss of neurofibromin. This allows cells to grow without control.
    www.mayoclinic.org/diseases-conditions/neurofibromatosis/symptoms-causes/syc-20350490
    www.mayoclinic.org/diseases-conditions/neurofibromatosis/symptoms-causes/s…
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    WEBJan 25, 2023 · Neurofibromatosis type 1 is caused by a loss of function mutation, either de novo or inherited, on the neurofibromin 1 (NF1 ) gene. It is located on band 17q11.2 and codes for neurofibromin.

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