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Short DNA or RNA moleculesLearn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.Oligonucleotides are short DNA or RNA molecules, oligomers, that have a wide range of applications in genetic testing, research, and forensics.en.wikipedia.org/wiki/Oligonucleotideoligonucleotide (plural oligonucleotides) a short sequence of nucleotides (RNA or DNA), typically with twenty or fewer base pairsen.wiktionary.org/wiki/oligonucleotide- People also ask
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See all on WikipediaOligonucleotide - Wikipedia
Oligonucleotides are short DNA or RNA molecules, oligomers, that have a wide range of applications in genetic testing, research, and forensics. Commonly made in the laboratory by solid-phase chemical synthesis, these small fragments of nucleic acids can be manufactured as single-stranded molecules with … See more
Oligonucleotides are chemically synthesized using building blocks, protected phosphoramidites of natural or chemically modified nucleosides or, to a lesser extent, of non … See more
Creating chemically stable short oligonucleotides was the earliest challenge in developing ASO therapies. Naturally occurring … See more
Cell uptake/internalisation still represents the biggest hurdle towards successful oligonucleotide (ON) therapeutics. A straightforward … See more
• Aptamers, oligonucleotides with important biological applications
• Morpholinos, oligos with non-natural backbones, which do … See more1981The first solid-phase chemical synthesis of oligonucleotides is reported by H. Gobind Khorana and coworkers1990sAntisense oligonucleotides are developed as potential therapeutic agents for genetic diseases1993The first DNA microarray is invented by Patrick O. Brown and David Botstein2006Janet Heasman uses Morpholino antisense oligonucleotides to knock down genes in vertebrates2016The first FDA-approved Morpholino drug, eteplirsen, is launched for the treatment of Duchenne muscular dystrophyAntisense oligonucleotides (ASO) are single strands of DNA or RNA that are complementary to a chosen sequence. In the case of See more
Chromatography
Alkylamides can be used as chromatographic stationary phases. Those phases have been … See more• Spingler B (January 2012). "Chapter 3. Metal-Ion-Promoted Conformational Changes of Oligonucleotides". In Sigel A, Sigel H, Sigel RK … See more
Wikipedia text under CC-BY-SA license Allele-specific oligonucleotide - Wikipedia
WEBAn allele-specific oligonucleotide ( ASO) is a short piece of synthetic DNA …
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What is an Oligonucleotide? - News-Medical.net
WEBJul 20, 2023 · Oligonucleotides are short nucleic acid polymers used in research, genetic testing and forensics. Oligonucleotides are usually made up of 13 to 25 nucleotides and are designed to hybridize...
Oligonucleotide Synthesis - an overview | ScienceDirect Topics
WEBOligonucleotides are short (typically <100 nt in length) sequences of single stranded …
Oligonucleotide Definition and Examples - Biology Online Dictionary
WEBJun 24, 2021 · Oligonucleotides are short DNA or RNA molecules. They readily bind to …
Oligonucleotide Therapeutics: From Discovery and Development …
WEBJan 22, 2022 · In this review, we focus on oligonucleotides designed to bind to RNA …
Oligonucleotide - an overview | ScienceDirect Topics
WEBOligonucleotides are short, single- or double-stranded DNA or RNA molecules, and …
Oligonucleotide - an overview | ScienceDirect Topics
WEBOligonucleotides are small molecules 8–50 nucleotides in length that bind via Watson …
Oligonucleotides - What Are They and Why Are They of Interest
WEBMay 26, 2020 · An oligonucleotide is a short chain of genetic information built from …
Oligonucleotide Standards | Biologics - US Pharmacopeia (USP)
WEBOligonucleotide Standards. Synthetic oligonucleotides are an emerging class of …
A Brief History of Oligonucleotide Synthesis - Springer Nature
WEBGait, M. J., Popov, S. G., Singh, M., and Titmas, R. C. (1980) Rapid synthesis of …
Oligonucleotide - WikiMili, The Best Wikipedia Reader
WEBOligonucleotides are short DNA or RNA molecules, oligomers, that have a wide range …
WEBThe history of chemical synthesis of oligonucleotides goes back to the discovery of …
What are Oligonucleotides? | Pharmaceutical Engineering - ISPE
WEBSep 12, 2018 · Oligonucleotides are short (20-25 bases typically) DNA or RNA …
What are Oligos? - Bachem
WEBOligonucleotides are short single or double-stranded fragments of DNA or RNA. In …
Oligonucleotide - an overview | ScienceDirect Topics
WEBOligonucleotides are short linear polymers of nucleotides that are individually …
IUPAC - oligonucleotides (O04287)
WEBFeb 24, 2014 · The IUPAC Compendium of Chemical Terminology.
Locked nucleic acid - Wikipedia
WEBA locked nucleic acid ( LNA ), also known as bridged nucleic acid (BNA), [1] and often …
Chemical Synthesis of Oligonucelotide Sequences: …
WEBMaintaining the sequence fidelity of synthetic oligonucleotides is critical to their use. …
Oligonucleotide synthesis - WikiMili, The Best Wikipedia Reader
WEBJan 29, 2024 · Oligonucleotides are short DNA or RNA molecules, oligomers, that have …
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