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  3. Cannabinoid receptor - Wikipedia

     
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    What are the different types of cannabinoid receptors?There are two known subtypes of cannabinoid receptors, termed CB 1 and CB 2. The CB 1 receptor is expressed mainly in the brain ( central nervous system or "CNS"), but also in the lungs, liver and kidneys. The CB 2 receptor is expressed mainly in the immune system, in hematopoietic cells, and in parts of the brain.
    What are cannabinoid receptor type 1 receptors?Cannabinoid receptor type 1 (CB 1) receptors are thought to be one of the most widely expressed G αi protein-coupled receptors in the brain.
    What are the endocannabinoid receptors?The biological effects of cannabinoids are mainly mediated by two members of the G-protein-coupled receptor family, cannabinoid receptors 1 (CB 1 R) and 2 (CB 2 R). The endocannabinoids, cannabinoid receptors, and the enzymes/proteins responsible for their biosynthesis, degradation, and re-updating constitute the endocannabinoid system.
    Is there a second brain cannabinoid receptor?The DNA sequence that encodes a G-protein -coupled cannabinoid receptor in the human brain was identified and cloned in 1990. These discoveries led to determination in 1993 of a second brain cannabinoid receptor named cannabinoid receptor type 2 or CB2.
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    WebCannabinoid Receptor 2 (CB2) is a G protein-coupled receptor (GPCR) with considerable, though as yet unrealised, therapeutic potential. Promising preclinical data supports the applicability of CB2 activation in …

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