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- Antisense small RNAs (abbreviated anti small RNA or anti-sRNA) are short RNA sequences (about 50-500 nucleotides long) that are complementary to other small RNA (sRNA) in the cell. sRNAs can repress translation via complementary base-pairing with their target mRNA sequence.
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See all on WikipediaAntisense RNA - Wikipedia
Antisense RNA (asRNA), also referred to as antisense transcript, natural antisense transcript (NAT) or antisense oligonucleotide, is a single stranded RNA that is complementary to a protein coding messenger RNA (mRNA) with which it hybridizes, and thereby blocks its translation into protein. … See more
Some of the earliest asRNAs were discovered while investigating functional proteins. An example was micF asRNA. While characterizing … See more
Antisense RNAs can be classified in different ways. In terms of regulatory mechanisms, some authors group asRNAs into RNA-DNA interactions, RNA-RNA interactions … See more
The initial asRNAs discovered were in prokaryotes including plasmids, bacteriophage and bacteria. For example, in plasmid ColE1, the asRNA termed RNA I plays an important … See more
Wikipedia text under CC-BY-SA license Antisense technology: an overview and prospectus - Nature
WEBMar 24, 2021 · Nine single-stranded antisense oligonucleotide (ASO) drugs representing four chemical classes, two mechanisms of action and four routes of administration have …
- Author: Stanley T Crooke, Brenda F Baker, Rosanne M Crooke, Xue-Hai Liang
- Publish Year: 2021
- Studies of Antisense RNA wikipedia
Antisense RNA: the new favorite in genetic research - PMC
WEBDec 6, 2017 · Antisense RNAs are unique DNA transcripts. They are small, noncoding, and diffusible molecules, containing 19–23 nucleotides that complement mRNA. With the …
- Author: Jian-zhong Xu, Jun-lan Zhang, Wei-guo Zhang
- DOI: 10.1631/jzus.B1700594
- Publish Year: 2018
- Published: 2018/10
Antisense therapy - Wikipedia
Antisense therapy is a form of treatment that uses antisense oligonucleotides (ASOs) to target messenger RNA (mRNA). ASOs are capable of altering mRNA expression through a variety of mechanisms, including ribonuclease H mediated decay of the pre-mRNA, direct steric blockage, and exon content modulation through splicing site binding on pre-mRNA. Several ASOs have been approved in the United States, the European Union, and elsewhere.
Wikipedia · Text under CC-BY-SA license- Estimated Reading Time: 8 mins
RNA interference - Wikipedia
WEBAntisense RNA produced intracellularly by an expression vector may be developed and find utility as novel therapeutic agents. [2] Two types of small ribonucleic acid (RNA) …
- Estimated Reading Time: 10 mins
Recent insights into the functions and mechanisms of antisense …
WEBJan 10, 2024 · The antisense RNA molecule is a unique DNA transcript consisting of 19–23 nucleotides, characterized by its complementary nature to mRNA. These antisense …
11.10: Antisense RNA - Biology LibreTexts
WEBMay 14, 2022 · Surprisingly, preparations of sense RNA often turn out to be as effective an inhibitor as antisense RNA. Why? It seems that the preparations of sense RNA often …
Antisense technology: A review - Journal of Biological …
WEBAntisense technology: A review. Stanley T. Crooke. Xue-Hai Liang. Brenda F. Baker. Rosanne M. Crooke. Open Access Published: February 15, 2021 DOI: https://doi.org/10.1016/j.jbc.2021.100416. Antisense technology: A …
Antisense RNA Therapeutics: A Brief Overview. - PMC
WEBNucleic acid therapeutics is a growing field aiming to treat human conditions that has gained special attention due to the successful development of mRNA vaccines against SARS …
WEBMar 24, 2021 · Nine single-stranded antisense oligonucleotide (ASO) drugs representing four chemical classes, two mechanisms of action and four routes of administration have …
Gene regulation by antisense transcription | Nature Reviews …
WEBNov 12, 2013 · Antisense expression can coordinate gene expression either in cis or in trans. Their ability to interact with other regulatory mechanisms emphasizes their …
Antisense RNA Therapeutics: A Brief Overview - PubMed
WEBRNA, Antisense. RNA, Messenger. Nucleic acid therapeutics is a growing field aiming to treat human conditions that has gained special attention due to the successful …
Antisense technology: an overview and prospectus - PubMed
WEBNine single-stranded antisense oligonucleotide (ASO) drugs representing four chemical classes, two mechanisms of action and four routes of administration have been …
Antisense RNA Design, Delivery, and Analysis [Internet].
WEBAntisense RNA Design, Delivery, and Analysis [Internet]. New York: Humana; 2022. Antisense RNA Design, Delivery, and Analysis [Internet]. Show details. Contents; …
Antisense technology: A review - ScienceDirect
WEBJan 1, 2021 · “Antisense” included an oligonucleotide of any structure or chemistry designed to bind target RNA via Watson–Crick hybridization. In practice, antisense …
Milestones in antisense RNA research - Nature
WEBNov 15, 2019 · An antisense oligonucleotide splicing modulator to treat spinal muscular atrophy. The United States Food and Drug Administration approves the first antisense …
Sense (molecular biology) - Wikipedia
WEBAn RNA sequence that is complementary to an endogenous mRNA transcript is sometimes called "antisense RNA". In other words, it is a non-coding strand complementary to the …
Antisense-RNA – Wikipedia
WEBDie Antisense-RNA ( aRNA ), auch natürliches Antisense Transkript (NAT) genannt, [1] ist eine einzelsträngige RNA, die komplementär zu einer proteincodierenden Messenger …
Anti small RNA - Wikipedia
WEBAntisense small RNAs (abbreviated anti small RNA or anti-sRNA) are short RNA sequences (about 50-500 nucleotides long) that are complementary to other small RNA …
Natural antisense transcripts as versatile regulators of gene ...
WEBApr 17, 2024 · Natural antisense transcripts (NATs) are RNAs transcribed from the opposite strand of genes and constitute a major subclass of regulatory long non-coding …
Category:Antisense RNA - Wikipedia
WEBCategory:Antisense RNA - Wikipedia. This category groups pages related to antisense RNA, which is cellular ribonucleic acid ( RNA) that regulates the expression by pairing …
In situ hybridisatie - Wikipedia
WEBHet gebruik van riboprobes, complementair-RNA, is ingeburgerd bij in situ hybridisatie van RNA, omdat sense- en antisense-monsters met hoge specificiteit kunnen worden geproduceerd met behulp van in vitro transcriptie. Een ander voordeel is dat niet-gehybridiseerd RNA kan worden afgebroken met behulp van RNase en weggewassen.
David Baulcombe - Wikipedia, la enciclopedia libre
WEBThe Processing and Intracellular Transport of Messenger RNA in a Higher Plant (1976) Información profesional; Área: científico, botánico, genetísta, profesor: Empleador: Universidad de Cambridge; ... Hamilton, A. J.; Baulcombe, DC (1999). «A Species of Small Antisense RNA in Posttranscriptional Gene Silencing in Plants». Science 286 ...
c4 antisense RNA - Wikipedia
WEBThe c4 antisense RNA is a non-coding RNA used by certain phages that infect bacteria. It was initially identified in the P1 and P7 phages of E. coli. [2] The identification of c4 …
VIM antisense RNA 1 - Wikipedia
WEB100507347 n/a Ensembl ENSG00000229124 n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) Chr 10: 17.21 – 17.23 Mb n/a PubMed search …
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